Common Supplement Shows Concerning Link to Heart Failure

Common Supplement Shows Concerning Link to Heart Failure

Recent research into a popular sleep aid has raised concerns about its long-term use. A new analysis of adults suffering from insomnia found that extended melatonin consumption might be linked to an increased risk of heart problems.

Study Overview

The study, which has not yet undergone peer review, examined data from over 130,000 adults across several countries. Results indicated that individuals prescribed melatonin for longer than one year had an 89 percent higher risk of heart failure over five years and were twice as likely to die from any cause compared to those who did not take the supplement.

“People prescribed melatonin for more than a year were at greater risk of heart issues,” researchers noted in the preliminary report.

Interpretation and Context

While these findings are concerning, scientists emphasize that the results are preliminary and do not warrant immediate changes to health guidelines. The findings do not necessarily prove that melatonin itself causes harm but suggest that extended use should be studied in greater depth.

“The results suggest that longer-term uses of melatonin need to be studied further to ensure they are safe.”

Current Medical Consensus

Melatonin remains widely regarded as safe for short-term use—typically one to two months—among adults who are not pregnant or breastfeeding. However, there is a shortage of data about its long-term effects, and experts argue that more research is needed given its growing popularity.

Presented Findings

The research was shared at the American Heart Association’s Scientific Sessions, highlighting the need for more rigorous studies into the prolonged use of melatonin and its potential effects on cardiovascular health.

Author’s summary: Preliminary research links long-term melatonin use to higher heart risks, stressing the need for deeper safety studies as this sleep aid gains popularity.

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ScienceAlert ScienceAlert — 2025-11-07