Internal Cooling System Improves Recovery After Brain Injury in Mice
Reducing mice’s body temperature immediately after brain injury improved their motor ability and coordination during recovery.
Cooling the brains of mice with traumatic brain injury by activating hibernation neurons helped them recover faster.
Cooling down a damaged brain can protect neurons by suppressing inflammation.1 However, lowering the body temperature externally can lead to complications such as impaired clotting and cardiac arrhythmias.
Researchers led by Takeshi Sakurai at the University of Tsukuba have found a way to leverage hypothermia without causing adverse effects by cooling the brain from within.
In a study published in The Journal of Neuroscience, Sakurai and his team showed that activating a specific population of hibernation neurons can protect the brains of mice from the worst effects of traumatic brain injury.
Cooling down a damaged brain can protect neurons by suppressing inflammation.
Author summary: Researchers find internal cooling improves brain injury recovery in mice.
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