Demetri Maxim's life was affected by kidney disease at a young age, when his mother's kidneys stopped working and she had to undergo dialysis.
Maxim's mother later received a kidney transplant, but he inherited Polycystic Kidney Disease (PKD) from her. About 1 in 7 Americans have Chronic Kidney Disease (CKD), with 10% of cases due to genetic conditions.
Maxim became determined to find a cure, and his breakthrough moment came in 2021 when Nature Magazine published a study showing that PKD can be reversed in mice using CRISPR technology.
Maxim has been obsessed with finding a cure for himself and others ever since he was in high school.
Learn more about Biotech Nephrogen's innovative approach at TechCrunch Disrupt 2025.
Author's summary: Biotech Nephrogen uses AI and gene therapy to fight kidney disease.