Breakthrough in Heterocycle Production
Researchers from Tomsk Polytechnic University (TPU) and St. Petersburg State University have developed a novel method to synthesize imidazoles, a class of valuable heterocycles, using oxygen from the air as a key reagent.
Imidazoles are a crucial component of various organic molecules used to create medications with a broad spectrum of action, including antiparasitic, antifungal, antibacterial, antitumor drugs, and high blood pressure medications.
The key reagent to produce imidazoles is oxygen, which can be obtained directly from the air.
The research, supported by a Russian Science Foundation grant, has been published in the journal SYNTHESIS (Q2, IF: 2.3), and is expected to reduce the cost and simplify the synthesis of imidazoles.
Imidazoles are an integral part of a wide range of organic molecules that serve as the basis for creating various drugs.
- Antiparasitic drugs
- Antifungal drugs
- Antibacterial drugs
- Antitumor drugs
- Medications for high blood pressure
Author's summary: TPU chemists develop method to produce valuable heterocycles using air.
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