Intracameral Antibiotics Reduce Endophthalmitis Risk in Patients With Capsular Ruptures

Intracameral Antibiotics Reduce Endophthalmitis Risk in Patients With Capsular Ruptures

Intracameral antibiotics significantly lower endophthalmitis risk in patients who experience posterior capsular rupture (PCR) during cataract surgery.

According to a study published in the Journal of Refractive Surgery, researchers conducted a systematic review and meta-analysis to evaluate the effectiveness of intracameral antibiotics (ICA) in reducing the risk of postoperative endophthalmitis (POE) in patients with PCR.

The study included eligible randomized controlled trials (RCTs) and observational studies that reported POE incidence in PCR patients with and without ICA prophylaxis, searching three databases up to May 21, 2024.

Intracameral antibiotics (ICA) significantly reduce the incidence of postoperative endophthalmitis (POE) in patients who experienced posterior capsular rupture (PCR) during cataract surgery.

Author's summary: ICA reduces endophthalmitis risk in cataract surgery patients.

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Ophthalmology Advisor Ophthalmology Advisor — 2025-10-30

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